{"id":10980,"date":"2022-03-07T11:29:52","date_gmt":"2022-03-07T10:29:52","guid":{"rendered":"https:\/\/sesc.cat\/?p=10980"},"modified":"2022-03-24T18:46:09","modified_gmt":"2022-03-24T17:46:09","slug":"injection-site-myositis-and-panniculitis","status":"publish","type":"post","link":"https:\/\/sesc.cat\/en\/injection-site-myositis-and-panniculitis\/","title":{"rendered":"Injection site myositis and panniculitis"},"content":{"rendered":"

We received an inquiry regarding 21, 12-months old, Montbeliard breed calves showing a focalized inflammatory process located in the right cervical area, affecting the braquiocefalic muscle. The localization and appearance of the lesions were compatible with lesions derived from a parenteral pharmacological administration.<\/p>\n

Muscle with lesions from 10 animals were submitted. Although variably, all of them presented similar lesions, ranging from 1 to 4 centimetres in diameter. They presented an indurated consistency, and featured a yellowish central area surrounded by a thick rim of pinkish tissue (fibrous tissue). Histopathological study was performed, which revealed chronic inflammatory and necrotizing lesions within the muscle and adipose panicle (myositis and panniculitis<\/strong>), with a prominent lymphoplasmacytic component (with pseudofollicular arrangement) and presence of eosinophilic amorphous material (presumably injected material).<\/p>\n

Although not fully conclusive, the inflammatory component of the lesions could suggest a vaccinal origin, as the local stimulation of the immune system elicits a lymphoplasmacytic reaction much greater than those seen in non-vaccine pharmacological reactions. At the documentation regarding the food-chain information it was recorded that these animals had been vaccinated 3 weeks prior to slaughter. The size, characteristics of the inflammatory infiltrate and chronicity of the lesions are compatible with the injection of a vaccinal product 3 weeks prior to slaughter, as detailed in the carcass documentation. (AC)<\/p>\n

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LThe fascia of this muscle was thickened and indurated focally, and at the cut section revealed yellowish material in the central area.<\/p><\/div>\n

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H<\/strong>istologic detail of the lesion. A prominent inflammatory reaction can be observed, mainly lymphoplasmacytic and to a lesser extent, macrophagic, in pseudofollicular disposition.<\/p><\/div>\n

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Scattered within the inflammation, accumulation of amorphous eosinophilic material can be seen, presumably injected material.<\/p><\/div>\n

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Similar lesion, in this case affecting mainly the muscle but in a similar manner. In the periphery of the lesion, the fibrosis is progresively replacing the muscular tissue.<\/p><\/div>\n

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Histologic detail of the periphery of the lesion above. Abundant fibrous tissue and lymphoplasmacytic inflammation can be seen replacing and surrounding the muscular fibers. .<\/p><\/div>\n

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Some of the lesions showed a cavitary appearance, in which the peripheric reaction was less prominent and presented a central cavity with fluid content.<\/p><\/div>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

We received an inquiry regarding 21, 12-months old, Montbeliard breed calves showing a focalized inflammatory process located in the right cervical area, affecting the braquiocefalic muscle.<\/p>\n","protected":false},"author":24311,"featured_media":10977,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[171,255],"tags":[401],"class_list":["post-10980","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bovine-2","category-muscle-bovine-2","tag-muscle-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts\/10980","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/users\/24311"}],"replies":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/comments?post=10980"}],"version-history":[{"count":0,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts\/10980\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/media\/10977"}],"wp:attachment":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/media?parent=10980"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/categories?post=10980"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/tags?post=10980"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}