{"id":5117,"date":"2012-11-12T16:18:57","date_gmt":"2012-11-12T15:18:57","guid":{"rendered":"https:\/\/sesc.cat\/lymphadenopathy-and-skin-lesions-in-pigs\/"},"modified":"2022-04-20T20:01:56","modified_gmt":"2022-04-20T19:01:56","slug":"lymphadenopathy-and-skin-lesions-in-pigs","status":"publish","type":"post","link":"https:\/\/sesc.cat\/en\/lymphadenopathy-and-skin-lesions-in-pigs\/","title":{"rendered":"Lymphadenopathy and skin lesions in pigs"},"content":{"rendered":"<ul>\n<li><strong>Lymphadenomegaly<\/strong>: enlarged lymph nodes.<\/li>\n<li><strong>Lymphadenitis<\/strong>: inflammation of lymph nodes, which when generalized is often an indicator of a systemic infectious disease in that carcass. However, this is not always the case.<\/li>\n<li><strong>Lymphadenopathy<\/strong>: term that refers to a non-specific change (at a macroscopic level) of the lymph nodes, that present with increased size and which may be regional or generalized.<\/li>\n<\/ul>\n<p>In this post we have tried to review the possible causes that can cause lymph node changes:<\/p>\n<ul>\n<li><strong>Benign lymphoid hyperplasia<\/strong>: nonspecific immune reaction in the lymph node, where no inflammatory exudate can be observed . It may be accompanied by oedema or congestion. It can be a physiological process or as a result of a viral, bacterial or protozoan infection. In pigs it may have cystic appearance due to the lobular architecture of their lymph nodes.<\/li>\n<li><strong>Stress Response<\/strong>: pigs respond in a peculiar manner to stress during handling. Poor management or overexcitement can cause hyperacute bleeding \/ blood reabsorption in lymph nodes and erythematous lesions of the skin and subcutis. These need to be distinguished from lesions associated with sepsis or viremia.<\/li>\n<li><strong>Lymphadenitis<\/strong>: presence of an inflammatory reaction in the lymph nodes, can be acute or chronic and can have different causes.\n<ul>\n<li><strong>Suppurative lymphadenitis<\/strong>: characterized by the presence of purulent exudate. Associated with bacterial infections<\/li>\n<li><strong>Necrotizing Lymphadenitis<\/strong>: presence of necrosis. Associated with <em>Salmonella typhisuis<\/em> infection , mycobacteria, fungi and Actinomycetal-type bacteria (<em>Nocardia spp<\/em>).<\/li>\n<li><strong>Granulomatous lymphadenitis<\/strong>: hardened, well defined or encapsulated nodules can be observed, sometimes mineralized (nodular form), or an increase in size without apparent macroscopic lesion (diffuse). Microscopically macrophage infiltration can be observed. The nodular form is compatible with TB, fungal or parasitic migration, the diffuse form is typical of PMWS.<\/li>\n<\/ul>\n<\/li>\n<li><strong>Neoplasia:<\/strong> can be primary (a malignant lymphoma is relatively common in pigs) or, less frequently, it might be a metastasis (carcinoma, mesothelioma, etc.).<\/li>\n<li>Other changes:\n<ul>\n<li><strong>Oedema<\/strong>: increased size and humid appearance when cut, remember that lymph nodes drain fluid extravasated from the tissues.<\/li>\n<li><strong>Reabsorption of blood \/ hemorrhage<\/strong>: dark reddish appearance, lymph nodes drain extravasated blood in the tissues. It can also be primary vascular damage due to viremia or sepsis. If it is blood drainage red areas correspond to peritravecular and subcapsular sinuses, while if it is bleeding itself the reddish coloration is diffuse throughout the lymph node parenchyma.<\/li>\n<li><strong>Emphysema<\/strong>: presence of air bubbles adhered to the lymph node itself, in pigs, associated with intestinal emphysema. Increase in size and they float in the water.<\/li>\n<li><strong>Hemosiderosis<\/strong>: hemosiderin deposits, mainly observed in subcapsular and peritravecular sinuses and especially visible in young animals that received injection of iron, giving a dark brown colouration to lymph nodes.<\/li>\n<li><strong>Anthracosis<\/strong>: deposits of carbon pigment giving a black discoloration.<\/li>\n<li><strong>Melanosis<\/strong>: congenital deposits of melanin pigment.<\/li>\n<li><strong>Ceroid pigment deposition<\/strong>: greenish, metabolism byproducts of lipid substances.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>List of most common diseases that may present with lymphadenopathy:<\/p>\n<table border=\"1\" width=\"640\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td colspan=\"2\" valign=\"top\" width=\"234\">\n<p align=\"center\"><strong><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Disease \/ Agent<\/span><\/span><\/strong><\/p>\n<\/td>\n<td valign=\"top\" width=\"170\">\n<p align=\"center\"><strong><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Localization<\/span><\/span><\/strong><\/p>\n<\/td>\n<td valign=\"top\" width=\"236\">\n<p align=\"center\"><strong><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Macroscopic lesion <\/span><\/span><\/strong><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td colspan=\"4\" width=\"640\"><strong><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">BACTERIA<\/span><\/span><\/strong><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><em><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Arcanobacterium pyogenes<\/span><\/span><\/em><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Widespread or focal<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Suppurative lymphadenitis.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><em><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Bacillus anthracis<\/span><\/span><\/em><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Mandibular and suprafaringeal LN.<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Increase in size.<\/span><\/span><\/p>\n<p><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Haemorrhage and necrosis.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td width=\"225\"><em><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Clostridium perfringens<\/span><\/span><\/em><\/td>\n<td colspan=\"2\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Peritoneal LN<\/span><\/span><\/td>\n<td width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Haemorrhage. Emphisema.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Exhudative epidermitis<\/span><\/span><\/p>\n<p><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">(<em>Staphylococcus hyicus<\/em>)<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Superficial LN<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Increase in size. Oedema.<\/span><\/span><\/p>\n<p><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Suppurative lymphadenitis.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Erysipelas<\/span><\/span><\/p>\n<p><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">(<em>Erysipelothrix rhusiopathiae<\/em>)<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Widespread<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Increase in size, congestion, subcapsular haemorrhage.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><em><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Mycoplasma hyopneumoniae<\/span><\/span><\/em><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Bronchial and mediastinic\u00a0LN\u00a0<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Increase in size.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><em><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Rhodococcus equi<\/span><\/span><\/em><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Cervical and submaxilar LN<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Necrotizing lymphadenitis<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Salmonelosis<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Peritoneal LN<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Oedema, haemorrhage and necrosis.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Septicaemia by <em>Escherichia coli<\/em><\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Starts in mesenteric LN<\/span><\/span><\/p>\n<p><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Widespread.<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Increase in size. Congestion.<\/span><\/span><\/p>\n<p><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">\u00a0<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Septicaemia by Salmonella<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Widespread, but particularly in gastrohepatic LN.<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Oedema and increase in size.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Septicaemia by <em>Streptococcus<\/em> (<em>S.equisimilis, S.suis<\/em>)<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Widespread or focal<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Increase in size.<\/span><\/span><\/p>\n<p><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Suppurative lymphadenitis.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Tuberculosis<\/span><\/span><\/p>\n<p><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">(<em>M. bovis, M. avium<\/em>)<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Widespread or focal<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Granulomatous\/necrotizing lymphadenitis.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td colspan=\"4\" width=\"640\"><strong><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">VIRUS<\/span><\/span><\/strong><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Aujeszky\u2019s disease<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Mainly in oral cavity and upper respiratory tract LN.<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Increase in size, Haemorrhage and necrosis.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Porcine Circovirosi (PMWS)<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Widespread<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Increase in size.<\/span><\/span><\/p>\n<p><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Granulomatous lymphadenitis.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Cytomegalovirus<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Thoracic LN<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Increase in size.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Japanese B encephalitis<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Widespread<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Congestion.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Porcine Influenza<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Bronchial and mediastinic LN.<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Increase in size.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Classical swine fever and other pestiviruses (BD, BVD)<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Widespread<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Increase in size, oedema and haemorrhages.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">African swine fever<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Widespread, mostly gastrohepatic LN.<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Increase in size, oedema and severe haemorrhages.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">PRRS<\/span><\/span><\/td>\n<td colspan=\"2\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Thoracic LN, Widespread<\/span><\/span><\/td>\n<td width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Oedema, brown colouration and increase in size.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td colspan=\"4\" width=\"640\"><strong><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">OTHERS<\/span><\/span><\/strong><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Toxoplasmosis<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Widespread<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Increase in size.<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"225\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Lymphoid neoplasias (Multicentric lymphoma, lymphosarcoma).<\/span><\/span><\/td>\n<td colspan=\"2\" valign=\"top\" width=\"180\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Widespread<\/span><\/span><\/td>\n<td valign=\"top\" width=\"236\"><span style=\"color: #504e53; font-family: 'Lucida Grande', 'Lucida Sans Unicode', verdana, arial, Tahoma, Verdana, sans-serif; font-size: small;\"><span style=\"line-height: normal;\">Increase in size.<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>When lymphadenopathy is observed other lesions must be looked for in the skin or viscera suggesting viremia or septicemia such as bleeding (petechiae, ecchymosis, purpura), pustules, papules, crusts &#8230;<\/p>\n<p>To diagnose these processes <strong>formalin fixed samples<\/strong> shoud be submitted of the affected skin, organs and lymph nodes. Keep in mind that the process of blanching the carcass causes significant artifacts to the skin and often precludes the obtention of an accurate diagnosis. To facilitate the diagnosis is also advisable to attach samples of the \u00a0unaffected skin of the same animal\u00a0to compare it with the lesioned parts.<\/p>\n<p>If septicaemia is suspected\u00a0liver or spleen samples can be submitted (organs with high blood content) refrigerated for microbiological culture.<\/p>\n<div id=\"attachment_1204\" style=\"width: 650px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/sesc.cat\/wp-content\/uploads\/2012\/11\/bc5045f16d72247_IMG_1548_WM.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-1204\" class=\"size-full wp-image-6393\" title=\"Moderate lymphadenomegalia and blood resorption (regional drainage). In this case the most likely cause was a dermatitis due to exposure to solar radiation with a secondary reactive lymph nodes hyperplasia.\" src=\"https:\/\/sesc.cat\/wp-content\/uploads\/2012\/11\/bc5045f16d72247_IMG_1548_WM.jpg\" alt=\"Moderate lymphadenomegalia and blood resorption (regional drainage). In this case the most likely cause was a dermatitis due to exposure to solar radiation with a secondary reactive lymph nodes hyperplasia.\" width=\"640\" height=\"480\" srcset=\"https:\/\/sesc.cat\/wp-content\/uploads\/2012\/11\/bc5045f16d72247_IMG_1548_WM.jpg 640w, https:\/\/sesc.cat\/wp-content\/uploads\/2012\/11\/bc5045f16d72247_IMG_1548_WM-300x225.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><p id=\"caption-attachment-1204\" class=\"wp-caption-text\">Moderate lymphadenomegalia and blood resorption (regional drainage). In this case the most likely cause was a dermatitis due to exposure to solar radiation with a secondary reactive lymph nodes hyperplasia.<\/p><\/div>\n<div id=\"attachment_1202\" style=\"width: 650px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/sesc.cat\/wp-content\/uploads\/2012\/11\/bc5045f16d72590_IMG_1555_WM.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-1202\" class=\"size-full wp-image-6389\" title=\"A second example of the case described in Figure 1.\" src=\"https:\/\/sesc.cat\/wp-content\/uploads\/2012\/11\/bc5045f16d72590_IMG_1555_WM.jpg\" alt=\"A second example of the case described in Figure 1.\" width=\"640\" height=\"480\" srcset=\"https:\/\/sesc.cat\/wp-content\/uploads\/2012\/11\/bc5045f16d72590_IMG_1555_WM.jpg 640w, https:\/\/sesc.cat\/wp-content\/uploads\/2012\/11\/bc5045f16d72590_IMG_1555_WM-300x225.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><p id=\"caption-attachment-1202\" class=\"wp-caption-text\">A second example of the case described in Figure 1.<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Lymphadenomegaly: enlarged lymph nodes. Lymphadenitis: inflammation of lymph nodes, which when generalized is often an indicator of a systemic infectious disease in that carcass. However, this is not always the case. Lymphadenopathy: term that refers to a non-specific change (at a macroscopic level) of the lymph nodes, that present with increased size and which may [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":6389,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[233,179,225],"tags":[397,399,398,367,402,404,410],"class_list":["post-5117","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lymphoid-porcine-2","category-porcine-2","category-skin-porcine-2","tag-infectious-en","tag-lymph-nodes-en","tag-lymphoid-en","tag-neoplasia-en","tag-parasites-en","tag-skin-en","tag-tb-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts\/5117","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/comments?post=5117"}],"version-history":[{"count":0,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts\/5117\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/media\/6389"}],"wp:attachment":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/media?parent=5117"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/categories?post=5117"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/tags?post=5117"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}