{"id":5207,"date":"2014-03-17T08:09:34","date_gmt":"2014-03-17T07:09:34","guid":{"rendered":"https:\/\/sesc.cat\/granulomatous-pneumonia-of-unknown-cause-in-a-pig\/"},"modified":"2022-03-24T18:56:38","modified_gmt":"2022-03-24T17:56:38","slug":"granulomatous-pneumonia-of-unknown-cause-in-a-pig","status":"publish","type":"post","link":"https:\/\/sesc.cat\/en\/granulomatous-pneumonia-of-unknown-cause-in-a-pig\/","title":{"rendered":"Granulomatous pneumonia (of unknown cause) in a pig"},"content":{"rendered":"<p>Microscopically these masses corresponded to an intense inflammatory infiltrate composed mostly by macrophages, scant eosinophils and a few multinucleated giant cells. Necrosis was not present. Sectionsof the mediastinal lymph node were also studied andthe same type of  inflammation was fouind in them. It is therefore a <strong>granulomatous proliferative pneumonia and lymphadenitis<\/strong>.<\/p>\n<p>Unfortunately the final cause of such an inflammatory reaction could not be determined. The tests performed included :<\/p>\n<ul>\n<li>Ruling out a  <strong>mycobacteriosis<\/strong>  by Ziehl-Neelsen staining (Negative) and  PCR against <em>M.tuberculosis<\/em>complex (Negative) and mycobacteria culture (Negative).<\/li>\n<li>The presence of <strong>fungal <\/strong>structures was also discarded by means of a Grocott staining (Negative).<\/li>\n<li>No presence of gram positive <strong>bacteria<\/strong> could be observed with Gram staining (Negative) and through standard microbiological culture (Negative).<\/li>\n<li>Morphologically , it was also ruled that it was a process associated to <strong>parasites<\/strong> or a <strong>neoplasia<\/strong>.<\/li>\n<\/ul>\n<p>If anyone has encountered similar cases or has an idea of what can cause this type of lesion, you are welcome to share it in the comments section at the end of this post.<\/p>\n<div id=\"attachment_2022\" style=\"width: 630px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-1.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-2022\" class=\"size-large wp-image-6799\" alt=\"The lesion affects all lung lobes and mediastinal lymph nodes.\" src=\"https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-1-scaled-800x600.jpg\" width=\"620\" height=\"465\" srcset=\"https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-1-scaled-800x600.jpg 800w, https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-1-scaled-300x225.jpg 300w, https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-1-scaled-768x576.jpg 768w, https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-1-scaled-1536x1152.jpg 1536w, https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-1-scaled-2048x1536.jpg 2048w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><\/a><p id=\"caption-attachment-2022\" class=\"wp-caption-text\">The lesion affects all lung lobes and mediastinal lymph nodes.<\/p><\/div>\n<div id=\"attachment_2023\" style=\"width: 630px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-2.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-2023\" class=\"size-large wp-image-6801\" alt=\"When sectioned the masses have a whitish homogeneous colouration.\" src=\"https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-2-800x600.jpg\" width=\"620\" height=\"465\" srcset=\"https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-2-800x600.jpg 800w, https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-2-300x225.jpg 300w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><\/a><p id=\"caption-attachment-2023\" class=\"wp-caption-text\">When sectioned the masses have a whitish homogeneous colouration.<\/p><\/div>\n<div id=\"attachment_2020\" style=\"width: 630px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-3.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-2020\" class=\"size-large wp-image-6795\" alt=\"Under the microscope one can observe a granulomatous inflammatory reaction with numerous multinucleated giant cells such as the one of the image.\" src=\"https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-3-750x600.jpg\" width=\"620\" height=\"496\" srcset=\"https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-3-750x600.jpg 750w, https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-3-300x240.jpg 300w, https:\/\/sesc.cat\/wp-content\/uploads\/2014\/03\/SESC-131-13-3.jpg 1280w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><\/a><p id=\"caption-attachment-2020\" class=\"wp-caption-text\">Under the microscope one can observe a granulomatous inflammatory reaction with numerous multinucleated giant cells such as the one of the image.<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Microscopically these masses corresponded to an intense inflammatory infiltrate composed mostly by macrophages, scant eosinophils and a few multinucleated giant cells. Necrosis was not present. Sectionsof the mediastinal lymph node were also studied andthe same type of inflammation was fouind in them. It is therefore a granulomatous proliferative pneumonia and lymphadenitis. Unfortunately the final cause [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":6797,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[179],"tags":[397,405,399,410,392],"class_list":["post-5207","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-porcine-2","tag-infectious-en","tag-lungs-en","tag-lymph-nodes-en","tag-tb-en","tag-thoracic-cavity-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts\/5207","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/comments?post=5207"}],"version-history":[{"count":0,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts\/5207\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/media\/6797"}],"wp:attachment":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/media?parent=5207"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/categories?post=5207"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/tags?post=5207"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}