{"id":5255,"date":"2015-04-29T17:29:20","date_gmt":"2015-04-29T16:29:20","guid":{"rendered":"https:\/\/sesc.cat\/splenomegaly-and-peritoneal-lesions-in-a-pig-carcass\/"},"modified":"2022-03-24T19:03:39","modified_gmt":"2022-03-24T18:03:39","slug":"splenomegaly-and-peritoneal-lesions-in-a-pig-carcass","status":"publish","type":"post","link":"https:\/\/sesc.cat\/en\/splenomegaly-and-peritoneal-lesions-in-a-pig-carcass\/","title":{"rendered":"Splenomegaly and peritoneal lesions in a pig carcass"},"content":{"rendered":"<p>The histopathological study showed, both in the spleen and in the peritoneal lesions, a neoplastic round cell proliferation surrounded by an abundant proliferation of connective tissue. Polymorphonuclear eosinophilic leukocytes could be observed infiltrating this tissue. Morphological diagnosis was compatible with a <strong>Mastocytoma<\/strong>.<\/p>\n<p>To confirm the diagnosis immunohistochemistry against C-kit receptor was done, with a positive outcome. Toluidin Blue stain revealed the presence of intracytoplasmic granules in the neoplastic mast cells.<\/p>\n<p>It is a rare neoplasm in pigs, we had previously described a case affecting the skin: <a href=\"https:\/\/sesc.cat\/cutaneous-mastocytoma-in-a-pig-carcass\/?lang=en\">Cutaneous Mastocytoma<\/a>.<\/p>\n<div id=\"attachment_2355\" style=\"width: 630px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-2.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-2355\" class=\"size-large wp-image-7029\" alt=\"Marked increase in size of the spleen, which presents a pale appearance.\" src=\"https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-2-scaled-800x600.jpg\" width=\"620\" height=\"465\" srcset=\"https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-2-scaled-800x600.jpg 800w, https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-2-scaled-300x225.jpg 300w, https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-2-scaled-768x576.jpg 768w, https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-2-scaled-1536x1152.jpg 1536w, https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-2-scaled-2048x1536.jpg 2048w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><\/a><p id=\"caption-attachment-2355\" class=\"wp-caption-text\">Marked increase in size of the spleen, which presents a pale appearance.<\/p><\/div>\n<div id=\"attachment_2356\" style=\"width: 630px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-3.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-2356\" class=\"size-large wp-image-7031\" alt=\"Detail of the marble-like appearance of the splenic parenchyma. \" src=\"https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-3-800x600.jpg\" width=\"620\" height=\"465\" srcset=\"https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-3-800x600.jpg 800w, https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-3-300x225.jpg 300w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><\/a><p id=\"caption-attachment-2356\" class=\"wp-caption-text\">Detail of the marble-like appearance of the splenic parenchyma.<\/p><\/div>\n<div id=\"attachment_2357\" style=\"width: 630px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-4.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-2357\" class=\"size-large wp-image-7033\" alt=\"Miliary nodular lesions in the serous membranes of the abdominal cavity (intestines, stomach, etc.) \" src=\"https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-4-800x600.jpg\" width=\"620\" height=\"465\" srcset=\"https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-4-800x600.jpg 800w, https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-4-300x225.jpg 300w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><\/a><p id=\"caption-attachment-2357\" class=\"wp-caption-text\">Miliary nodular lesions in the serous membranes of the abdominal cavity (intestines, stomach, etc.)<\/p><\/div>\n<div id=\"attachment_2353\" style=\"width: 609px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-1.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-2353\" class=\"size-large wp-image-7025\" alt=\"Histopathological study. A: H&#038;E staining shows neoplastic mast cells surrounded by a fibrous matrix and presence of eosinophils infiltrating the mass (arrowhead). B: These mast cells were positive for the immunohistochemical marker against C-kit receptor. C: Toluidine blue staining showed the presence of intracytoplasmic granules.\" src=\"https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-1-599x600.jpg\" width=\"599\" height=\"600\" srcset=\"https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-1-599x600.jpg 599w, https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-1-150x150.jpg 150w, https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-1-300x300.jpg 300w, https:\/\/sesc.cat\/wp-content\/uploads\/2015\/04\/SESC-040-15-1-90x90.jpg 90w\" sizes=\"auto, (max-width: 599px) 100vw, 599px\" \/><\/a><p id=\"caption-attachment-2353\" class=\"wp-caption-text\">Histopathological study. <strong>A: <\/strong>H&#038;E staining shows neoplastic mast cells surrounded by a fibrous matrix and presence of eosinophils infiltrating the mass (arrowhead). <strong>B:<\/strong> These mast cells were positive for the immunohistochemical marker against C-kit receptor. <strong>C:<\/strong> Toluidine blue staining showed the presence of intracytoplasmic granules.<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>The histopathological study showed, both in the spleen and in the peritoneal lesions, a neoplastic round cell proliferation surrounded by an abundant proliferation of connective tissue. Polymorphonuclear eosinophilic leukocytes could be observed infiltrating this tissue. Morphological diagnosis was compatible with a Mastocytoma. To confirm the diagnosis immunohistochemistry against C-kit receptor was done, with a positive [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":7027,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[233,227,179],"tags":[],"class_list":["post-5255","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lymphoid-porcine-2","category-neoplasia-porcine-2","category-porcine-2"],"acf":[],"_links":{"self":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts\/5255","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/comments?post=5255"}],"version-history":[{"count":0,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts\/5255\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/media\/7027"}],"wp:attachment":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/media?parent=5255"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/categories?post=5255"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/tags?post=5255"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}