{"id":5289,"date":"2016-01-25T15:38:55","date_gmt":"2016-01-25T14:38:55","guid":{"rendered":"https:\/\/sesc.cat\/skin-neoplasia-in-a-calf\/"},"modified":"2022-04-20T19:54:44","modified_gmt":"2022-04-20T18:54:44","slug":"skin-neoplasia-in-a-calf","status":"publish","type":"post","link":"https:\/\/sesc.cat\/en\/skin-neoplasia-in-a-calf\/","title":{"rendered":"Skin Neoplasia in a calf"},"content":{"rendered":"

In a cross-breed 10 months old calf, multiple nodular alopecic lesions were observed on the skin.<\/strong><\/p>\n

The histopathological study evidenced a neoplastic proliferation infiltrating the epidermis and dermis structures consisting of a population of round cells with abundant cytoplasm. In a few of them, brownish granules could be spotted. \u00a0Infiltrating the neoplastic population, some eosinophil polymorphonuclear leukocytes could be observed.<\/p>\n

Immunohistochemical markers for B (CD79) and T lymphocytes (CD3) were performed with a negative result. The toloudine blue stain did not allow to identify the presence of intracytoplasmic granules. Instead, C-kit marker gave a positive result in 100% of neoplastic cells.<\/p>\n

The C-kit positive result and the presence of eosinophils infiltrating the mass support the diagnosis of a cutaneous mastocytoma. Negative results to lymphocytes markers help rule out a lymphoma. It is not possible however, to rule out that it is an amelanotic melanoma<\/strong> since these tumors can also react to the c-kit, but the presence of eosinophils tilts in favor of a mastocytoma.<\/p>\n

\"Gross

Gross appearance of the tumor. A:<\/strong> Multiple alopecic skin nodules. B:<\/strong> Detail of one of the nodules. C:<\/strong> Cross section of one of the nodules, the tumor invades the structures of the dermis.<\/p><\/div>\n

\"Estudi

Histopathological study<\/strong>. A:<\/strong> H&E. Neoplastic growth infiltrating the structures of the dermis. B:<\/strong> Immunohistochemistry against the marker C-Kit, with a positive result in all neoplastic cells. C:<\/strong> H&E. Eosinophils polimorfonucelar leukocytes can be observed (arrowheads) infiltrating the neoplastic population.<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

In a cross-breed 10 months old calf, multiple nodular alopecic lesions were observed on the skin.<\/p>\n","protected":false},"author":6,"featured_media":7189,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[171,243],"tags":[367,404],"class_list":["post-5289","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bovine-2","category-skin-bovine-2","tag-neoplasia-en","tag-skin-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts\/5289","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/comments?post=5289"}],"version-history":[{"count":0,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts\/5289\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/media\/7189"}],"wp:attachment":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/media?parent=5289"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/categories?post=5289"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/tags?post=5289"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}