{"id":5347,"date":"2017-02-02T09:46:36","date_gmt":"2017-02-02T08:46:36","guid":{"rendered":"https:\/\/sesc.cat\/mystery-dermatitis-volume-2\/"},"modified":"2022-03-24T19:04:58","modified_gmt":"2022-03-24T18:04:58","slug":"mystery-dermatitis-volume-2","status":"publish","type":"post","link":"https:\/\/sesc.cat\/en\/mystery-dermatitis-volume-2\/","title":{"rendered":"Mystery Dermatitis. Volume 2."},"content":{"rendered":"<p><strong>In a male, cross breed, 6 months old, pig carcass\u00a0multiple, multifocal, \u00a0erythematous lesions were observed some of which \u00a0with concentric circles morphology. Generalized lymphadenopathy\u00a0was also observed with increased size and redness of the lymph nodes.<\/strong><!--more--><\/p>\n<p>Samples submitted for histopathology were taken after scalding, precluding an appropriate assessment of the histological lesions in the epidermis and the superficial dermis due to the artifacts caused by this process. In the deeper dermis, \u00a0<strong>perivascular and periadnexal dermatitis<\/strong> was observed. The lymph nodes were hyperplastic and with abundant presence of eosinophilic polymorphonuclear leukocytes. The kidneys showed no obvious lesions.<\/p>\n<p>Despite having a very characteristic lesional pattern the aetiology could not be determined. A while ago another case of <a href=\"https:\/\/sesc.cat\/mystery-dermatitis\/?lang=en\">Mystery dermatitis<\/a> in a pig carcass was submitted, of which the ethiology could not be determined, in that case the lesions were radial.<\/p>\n<p>The differential diagnosis could include:<\/p>\n<ul>\n<li><a href=\"https:\/\/sesc.cat\/porcine-dermatitis-and-nephropathy-syndrome-pdns\/?lang=en\">Porcine Dermatitis and nephropathy syndrome<\/a> (PDNS): histopathological study of the kidneys ruled this one out, which was the main suspicion of the inspectors who submitted the case.<\/li>\n<li><a href=\"https:\/\/sesc.cat\/cutaneous-skin-lesions-in-swine\/?lang=en\">Pityriasis rosea<\/a>: swine juvenile psoriasiform pustular dermatitis. It seems one of the most probable differentials.<\/li>\n<li>Dermatophytosis (ringworm).<\/li>\n<li>Erysipelas: despite \u00a0the characteristic rhomboid morphology of lesions was not observed.<\/li>\n<\/ul>\n<p>In human medicine <strong>figured\u00a0erythemas<\/strong> are described, some of which (eg <em>erythema annulare centrifugum<\/em>) are reminiscent of images we see in this pig carcass. The causes can be varied: from primary disease of the skin (tinea, urticaria &#8230;) to systemic diseases (bacterial infections, neoplasms &#8230;) presenting this lesion.<\/p>\n<p>Again, if any of you have seen such a lesion, we\u00a0encourage you to discuss this in the comments section at the end of this post.<\/p>\n<div id=\"attachment_3249\" style=\"width: 347px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-3249\" class=\"size-large wp-image-7451\" src=\"https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-5-scaled-337x600.jpg\" alt=\"Lesions a l\u2019aspecte ventral de la canal.\" width=\"337\" height=\"600\" srcset=\"https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-5-scaled-337x600.jpg 337w, https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-5-scaled-169x300.jpg 169w, https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-5-scaled-768x1367.jpg 768w, https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-5-scaled-863x1536.jpg 863w, https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-5-scaled-1150x2048.jpg 1150w, https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-5-scaled.jpg 1438w\" sizes=\"auto, (max-width: 337px) 100vw, 337px\" \/><p id=\"caption-attachment-3249\" class=\"wp-caption-text\">Lesions on the ventral aspect of the carcass.<\/p><\/div>\n<div id=\"attachment_3248\" style=\"width: 347px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-3248\" class=\"size-large wp-image-7449\" src=\"https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-4-337x600.jpg\" alt=\"Detall de les lesions a la part dorsal, que mostren un particular patr\u00f3 conc\u00e8ntric.\" width=\"337\" height=\"600\" srcset=\"https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-4-337x600.jpg 337w, https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-4-168x300.jpg 168w, https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-4-768x1368.jpg 768w\" sizes=\"auto, (max-width: 337px) 100vw, 337px\" \/><p id=\"caption-attachment-3248\" class=\"wp-caption-text\">Detail of the \u00a0lesions on the dorsal aspect, showing a particular concentric pattern.<\/p><\/div>\n<div id=\"attachment_3251\" style=\"width: 347px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-3251\" class=\"size-large wp-image-7455\" src=\"https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-1-337x600.jpg\" alt=\"Augment de mida i envermelliment dels n\u00f2duls limf\u00e0tics inguinals superficials.\" width=\"337\" height=\"600\" srcset=\"https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-1-337x600.jpg 337w, https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-1-168x300.jpg 168w, https:\/\/sesc.cat\/wp-content\/uploads\/2017\/01\/SESC-077-16-1-768x1368.jpg 768w\" sizes=\"auto, (max-width: 337px) 100vw, 337px\" \/><p id=\"caption-attachment-3251\" class=\"wp-caption-text\">Increased size and redness of the superficial inguinal lymph nodes.<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>In a male, cross breed, 6 months old, pig carcass\u00a0multiple, multifocal, \u00a0erythematous lesions were observed some of which \u00a0with concentric circles morphology. Generalized lymphadenopathy\u00a0was also observed with increased size and redness of the lymph nodes.<\/p>\n","protected":false},"author":6,"featured_media":7453,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[179,225],"tags":[399,404],"class_list":["post-5347","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-porcine-2","category-skin-porcine-2","tag-lymph-nodes-en","tag-skin-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts\/5347","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/comments?post=5347"}],"version-history":[{"count":0,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/posts\/5347\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/media\/7453"}],"wp:attachment":[{"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/media?parent=5347"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/categories?post=5347"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sesc.cat\/en\/wp-json\/wp\/v2\/tags?post=5347"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}